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College of Agriculture
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Veterinary Molecular Biology
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Research
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Vaccines & Therapeutics
Department of Veterinary Molecular Biology
Vaccines and Therapeutics
Vaccines and therapeutics are the end-products of biomedical research. VMB researchers are developing new approaches to vaccinate against
infectious diseases of people and animals, and are also invesitgating therapeutic approaches to prevent damaging over-reactions of the immune system.
Harmsen Lab |
Research focuses on understanding aspects of immune responses unique to the lung. This includes the investigation of immune-mediated lung damage in Pneumocystis pneumonia, the effects of lung infections on development of asthma, and the use of nanotechnology for delivery of anti-inflammatory drugs to the lungs.
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Jutila Lab
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Recent efforts are focused on using high-throughput functional genomic analyses to gain insights into innate immune cell responses that can be targeted in the development of new prophylactic and therapeutic immune stimulants.
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Lei Lab |
Investigates the pathogenesis of bacterial pathogens group A Streptococcus and Streptococcus equi. Multidisciplinary approaches are used to identify novel virulence factors and elucidate their functions and pathogenic roles. We also search for new protective antigens of the pathogens and develop a nanoparticle-based adjuvant with ultimate goals of developing subunit vaccines against infections caused by these and other pathogens. |
Pascual Lab
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We are interested in learning how to adapt vaccines for mucosal immunizations
using targeted delivery systems. We hypothesize that by improved vaccine targeting we can
enhance vaccine uptake and efficacy. Current systems are adapting targeted delivery of vaccines
for Salmonella, Brucella, Yersinia, and botulinum as well as for autoimmune diseases, multiple
sclerosis and arthritis.
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